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. Author manuscript; available in PMC: 2017 Dec 25.
Published in final edited form as: Adv Genet. 2016 Jan 25;93:147–190. doi: 10.1016/bs.adgen.2015.11.004

Figure 4. Matching the genetic signatures of gene expression traits (eQTLs) to that of the disease trait to identify gene expression-disease associations.

Figure 4

Ui: binary indicator variables to represent the true SNP-gene expression causal relationship;, Vi: binary indicator variables for the true SNP-disease relationship. Z is a binary variable indicating whether the gene expression trait influences the disease.