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. Author manuscript; available in PMC: 2018 Jun 11.
Published in final edited form as: Nat Genet. 2017 Dec 11;50(1):54–61. doi: 10.1038/s41588-017-0005-8

Figure 5. Power to detect a genetic effect in a single-variant single-gene test depends on sample size, allelic effect size, and gene expression variability.

Figure 5

(a) TPR as a function of allelic fold change for five different numbers of replicates (half the total sample size). (b) TPR as a function of CV for five bins of allelic fold change, with 10 samples of each genotype.

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