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Epstein–Barr virus (EBV) and cytomegalovirus (CMV) co-infection is associated with higher proportions of CD27−IgD− B-cells at 5 years of age. From left to right, the proportions of CD27−IgD−, CD27+IgD+, and CD27+IgD− cells among CD19+ cells. EBV− (n = 15), EBV+CMV− (n = 5), and EBV+CMV+ (n = 15).
