Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 21;8:926. doi: 10.3389/fphar.2017.00926

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Li, Zong, Zhang, Zhang, Xu, Liang, Yang, Yong and Qian.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Orientin inhibits MI-induced apoptosis. TUNEL staining (A) and quantitation (B) in the hearts of vehicle and orientin-treated mice at 4 weeks post-MI (n = 6). (C,D) Representative Western blots and quantitation of Bax, Bcl-2, and C-caspase3 in the heart tissue of vehicle and orientin-treated mice at 4 weeks after sham or MI surgery (n = 6); ^∗p < 0.05 vs. vehicle-sham; ^#p < 0.05 vs. vehicle-MI. (E–I) NRCMs were pretreated with orientin (1, 5, 15, 30 μM) for 12 h, then exposed to hypoxia for 24 h. (E) MTT assays were performed to detect cell viability (n = 5, ^∗p < 0.05 vs. hypoxia-0 μM group). Annexin V staining (F) and quantitation (G) in the indicated group (n = 6). Representative Western blots (H) and quantitation (I) of Bax, Bcl-2, and C-caspase3 in the indicated group (n = 6); ^∗p < 0.05 vs. vehicle-normoxia; ^#p < 0.05 vs. vehicle-hypoxia.