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. 2017 Dec 21;5(24):e13531. doi: 10.14814/phy2.13531

Figure 9.

Figure 9

CoCl2 added to apical media on day 18. Data shows that application of CoCl2 in apical media does not cause a significant chronic change in (top) TER values or (bottom) I eq values of differentiated mCCD monolayers. N = 5–8. In the TER and I eq data, One‐way ANOVA shows no significant (P > 0.05) TER and Ieq changes among control groups. In the TER plot, * denotes significant change (P < 0.05) among 0 μmol/L CoCl2, 50, and μmol/L 100 CoCl2 treatment at a specific time‐point. # denotes CoCl2 treatment causes significant change (P < 0.05) between CoCl2‐treated sample at a specific time point with CoCl2‐treated or control sample at a different time point. Not all significance (#) are shown in the graph; all # are marked onto any noticeable change and applicable to group treated with CoCl2. There is no significant effect (P > 0.05) of apical application of 0, 50, or 100 μmol/L CoCl2 on I eq.