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. 2017 Dec 15;5(24):e13538. doi: 10.14814/phy2.13538

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© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Eosinophils are more numerous in small noncartilaginous airways compared to large cartilaginous airways. (A) Small noncartilaginous airways contained significantly more eosinophils than large cartilaginous airways. This difference was observed in all treatment groups and at all time points after exposure. (B) Small airways also contained more nerve‐associated eosinophils than large airways. A greater proportion of total airway eosinophils were associated with nerves in small airways (30%) compared to large (20%). N = 14. Data represent mean ± SEM. P < 0.05. Connecting lines distinguish individual animals. All treatment groups are represented in this analysis.