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. 2017 Aug 7;22(1):195–206. doi: 10.1111/jcmm.13308

Figure 2.

Figure 2

Upper lamina propria (ULP). PDGFRα (green) and αSMA (red) labelling. (A, D, G, K) controls. The ULP is made by several rows of cells. Those forming the first row immediately beneath the urothelium are PDGFRα+/αSMA− and form a continuous monolayer. The lower rows are made by PDGFRα+/αSMA− and PDGFRα+/αSMA+ cells. Asterisks in A indicate three myofibroblasts. (B, C, E, F, H, I, J) NDO patients. The suburothelial layer is maintained in all the patients. In the non‐responder patient, the ULP is very thick (C, F) and the upper portion is made by several rows of PDGFRα+/αSMA− cells while those located in the lower portions are mainly PDGFRα+/αSMA+ (C, F, J). U: urothelium. DLP: deep lamina propria. Calibration bar: A–C = 100 μm; D–F = 50 μm; G, H = 25 μm; K–J = 10 μm.