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Effect of RosA on IL‐1β‐induced phosphorylation of MAPKs in chondrocytes. Cells were pre‐incubated with various concentrations of RosA for 2 hrs, followed by stimulation with IL‐1β (10 ng/ml) for 30 min. Phosphorylation of extracellular signal‐regulated kinase (ERK), p38 and c‐jun amino‐terminal kinase (JNK) was assessed by Western blot. Data are expressed as mean ± standard deviation (SD). *P < 0.05 compared with cells stimulated with IL‐1β only.
