Figure 4.
The Ego-TC complex corresponds to half of the Ragulator complex. (a) Structure of the previously reported Ego-TC complex. The Ego1, Ego2 and Ego3 subunits are colored in limon, orange and pink, respectively. (b) Structure of the Lamtor1-α3-Lamtor5-Lamtor2 subcomplex, which is highly similar in the overall assembly of the Ego-TC complex. Lamtor1-α3, Lamtor5 and Lamtor2 are colored in green, red and magenta, respectively, and their spatial positions correspond to those of Ego1, Ego2 and Ego3, respectively.