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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Stem Cells. 2017 Sep 29;35(12):2366–2378. doi: 10.1002/stem.2707

Figure 5. Podocalyxin regulates microvillus formation and cell spacing in mouse podocytes.

Figure 5

(A) Schematic of knockout mouse generation and analysis. (B) TEM images of podocytes from Podxl−/− prenatal mice (E18.5), or age-matched littermate controls. Images from two representative experiments are shown. Zoom is shown to the right for dashed boxed regions. m, microvilli; J, junctions. (C) Quantification of microvillus number and (D) cell separation in Podxl−/− podocytes and littermate controls, with associated p-values. Each point represents a single podocyte (n = 4 control and 5 Podxl−/− mice). Scale bars, 5 μm.