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. Author manuscript; available in PMC: 2017 Dec 26.
Published in final edited form as: Cytokine. 2016 Jun 14;85:109–119. doi: 10.1016/j.cyto.2016.06.014

Figure 5.

Figure 5

The effects of H2O2 or 4-HNE on LPS- or TNF-α-induced pro-inflammatory cytokine expression in Kupffer cells or hepatocytes. A. Pro-inflammatory cytokine expression in Kupffer cells treated with 100μmol/l H2O2 or 5μmol/l 4-HNE for 24 hr followed by 0.2 ng/ml LPS for another 2 hr. B. Pro-inflammatory cytokine expression in hepatocytes treated with 100μmol/l H2O2 or 10μmol/l 4-HNE for 24 hr followed by 25 pg/ml TNF-α for another 2 hr. Relative mRNA levels of pro-inflammatory cytokines were determined by qPCR. Data are expressed as the mean ± SEM (n = 3). * P < 0.05 versus control, ǂ P < 0.05 versus H2O2 only; † P < 0.05 versus 4-HNE only; § P < 0.05 versus LPS only (panel A) or TNF-α only (panel B).