Table 2.
Allele and haplotype frequency of two CSMD1 genetic variants in the total sample and in the lower (Q1) and upper (Q4) quartiles of the MoCA distribution.
| Allele, haplotype | Total sample, N = 708 | Lower quartile (MoCA ≤ 20), N = 188 | Upper quartile (MoCA ≥ 25), N = 193 | Q1 versus Q4, p |
|---|---|---|---|---|
| rs1050325 | ||||
| C | 0.733 | 0.741 | 0.749 | 0.799 |
| A | 0.267 | 0.259 | 0.251 | |
|
| ||||
| rs2616984 | ||||
| A | 0.726 | 0.754 | 0.674 | 0.014 |
| G | 0.274 | 0.246 | 0.326 | |
|
| ||||
| rs1050325/rs2616984 haplotypes | ||||
| CA | 0.524 | 0.557 | 0.497 | 0.101 |
| CG | 0.209 | 0.184 | 0.251 | 0.024 |
| AA | 0.201 | 0.197 | 0.176 | 0.455 |
| AG | 0.065 | 0.062 | 0.075 | 0.478 |