Table 1.
Univariate analysis of the clinical characteristics of bloodstream infections caused by CRE and non-CRE.
| Clinical characteristics | Bloodstream infections with Enterobacteriaceae, n (%) | P value | |
|---|---|---|---|
| CRE group (n = 26) | Non-CRE group (n = 122) | ||
| Gender (male) | 16 (61.5) | 59 (48.4) | 0.222 |
| Age > 60 years | 22 (84.6) | 83 (68.0) | 0.091 |
| Community acquired | 0 | 30 (24.6) | 0.005∗ |
| Admission to the ICU | 20 (76.9) | 10 (8.2) | <0.001∗ |
| Long-term bedbound | 19 (73.1) | 61 (50) | 0.032∗ |
| Medical institution admission history within 3 months | 17 (65.4) | 75 (61.5) | 0.709 |
| Underlying diseases | |||
| Cardiovascular disease | 19 (73.1) | 54 (44.3) | 0.008∗ |
| Cerebrovascular disease | 21 (80.8) | 57 (46.7) | 0.002∗ |
| Chronic respiratory disease | 6 (23.1) | 9 (7.4) | 0.040∗ |
| Chronic kidney disease | 13 (50.0) | 33 (27.0) | 0.022∗ |
| Diabetes mellitus | 9 (34.6) | 44 (36.1) | 0.889 |
| Malignant tumor | 4 (15.4) | 44 (36.1) | 0.041∗ |
| Anemia | 26 (100.0) | 87 (71.3) | 0.002∗ |
| Hypoalbuminemia | 26 (100.0) | 98 (80.3) | 0.029∗ |
| Lung infection | 22 (84.6) | 61 (50.0) | 0.001∗ |
| Urinary tract infection | 12 (46.2) | 62 (50.8) | 0.666 |
| Abdominal infection | 5 (19.2) | 14 (11.5) | 0.453 |
| Tracheotomy | 12 (46.2) | 21 (17.2) | 0.001∗ |
| Liver dysfunction | 13 (50.0) | 24 (19.7) | 0.001 |
| Invasive surgery before infection | |||
| Mechanical ventilation | 18 (69.2) | 12 (9.8) | <0.001∗ |
| Central venous catheterization | 19 (73.1) | 28 (23.0) | <0.001∗ |
| Indwelling urethral catheterization | 25 (96.2) | 45 (36.9) | <0.001∗ |
| Sources of bloodstream infection | |||
| Catheter related | 10 (38.5) | 23 (18.9) | 0.029∗ |
| Respiratory system | 11 (42.3) | 26 (21.3) | 0.025∗ |
| Urinary tract infection | 0 (0) | 42 (34.4) | <0.001∗ |
| Others | 5 (19.2) | 31 (25.4) | 0.505 |
| Prior use of broad-spectrum antibiotics within 30 days | 25 (96.2) | 39 (32.0) | <0.001∗ |
| Combined fungal infection | 10 (38.5) | 10 (8.2) | <0.001∗ |
| Prior use of glucocorticoids within 30 days | 8 (30.8) | 11 (9.0) | 0.007∗ |
| Total length of hospital stay | 25.4 ± 11.1 | 21.0 ± 12.7 | 0.102 |
| 30-Day mortality rate | 17 (65.4) | 21 (17.2) | <0.001∗ |
| 48-Hour mortality rate | 6 (23.1) | 3 (2.5) | <0.001∗ |
ICU: intensive care unit; ∗P < 0.05.