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Co-localization of Rab7 with Aβ and PI3KC3 complex components in 12-month-old APP/PS1 mice. (a) Co-localization of Rab7 (green) and 6E10 (red) in 12-month-old APP/PS1 (Tg) cortex (n = 4) scale bar = 80 μm. (b) Co-localization of Rab7 (green) and Beclin1 or UVRAG (red) in 12-month-old Tg cortex (n = 4) scale bar = 40 μm. Aβ: Amyloid-β; Tg: Transgenic; PI3KC3: Class III phosphatidylinositol 3-kinase.
