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mRNA expression levels of Mfn2 and procollagen in the POP and NPOP fibroblasts
| Group | Mfn2 | Procollagen | ||
|---|---|---|---|---|
| 1A1 | 1A2 | 3A1 | ||
| POP (n = 10) | 0.76 ± 0.21 | 0.70 ± 0.19 | 0.82 ± 0.22 | 0.55 ± 0.13 |
| NPOP (n = 10) | 0.53 ± 0.17 | 0.95 ± 0.25 | 1.26 ± 0.34 | 0.78 ± 0.23 |
| t | 2.425 | −2.165 | −2.741 | −2.147 |
| P | 0.032 | 0.041 | 0.026 | 0.045 |
Compared to the NPOP, in the POP fibroblasts, the mRNA of Mfn2 was increased, while mRNA of procollagen was decreased. POP: Pelvic organ prolapse; NPOP: Non-POP; Mfn2: Mitofusin 2.
