Table 5.
Protein expression levels of Mfn2 and procollagen in the POP and NPOP fibroblasts
| Group | Mfn2 | Procollagen | ||
|---|---|---|---|---|
| 1A1 | 1A2 | 3A1 | ||
| POP (n = 10) | 0.84 ± 0.17 | 0.88 ± 0.21 | 0.93 ± 0.29 | 0.54 ± 0.13 |
| NPOP (n = 10) | 0.53 ± 0.15 | 1.20 ± 0.29 | 1.31 ± 0.38 | 0.91 ± 0.23 |
| t | 2.392 | −2.418 | −2.405 | −2.470 |
| P | 0.037 | 0.029 | 0.033 | 0.012 |
Compared to the NPOP, in the POP fibroblasts, the protein expression of Mfn2 was increased, while procollagen expression was decreased. POP: Pelvic organ prolapse; NPOP: Non-POP; Mfn2: Mitofusin 2.