Table 3.

Compounds which exhibit a measurable AmpG-specific activity index.

entry	ID	structure	analysis
1	SR-01000076250-2		Inorganic dye: poor drug-likeness and poorly-suited for follow-up
2	SR-05000002238-3		Patulin: natural product mycotoxin produced by a variety of molds. In ring-opened form it is chemically reactive, forming Schiff bases with biological amines.
3	SR-01000320782-1		A synthetic compound: phenolic hydrazones are structure alerts and thus modifications to the structure in probe development would be desirable
4	SR-05000002074-1		Natural product Polymyxin B, primarily used for resistant gram-negative infections. It is derived from the bacterium Bacillus polymyxa.
5	SR-01000226538-1		A synthetic compound in the aryl guanidine class. No stability or reactivity concerns.
6	SR-01000115944-1		A synthetic compound in the 7-aminomethyl 8-hydroxyquinoline class. These are known as “Betti bases” and may be chemical unstable to retro-Michael addition. More chemically stable analogs would be preferred.
7	SR-01000115950-1		A structural isomer also in the 7-aminomethyl 8-hydroxyquinoline class. More chemically stable analogs would be preferred.
8	SR-01000520919-1		A synthetic compound in the N-aryl sulfonamide class. No stability or reactivity concerns.