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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Ann Surg. 2017 Jun;265(6):1183–1191. doi: 10.1097/SLA.0000000000001830

Figure 5. I3C added to the diet reduces bacterial translocation during CDI.

Figure 5

Bacterial counts from tissue homogenates of (A) spleen, (B) lung, (C) liver and (D) kidney on day 4 following CDI in mice fed diet or diet + I3C. (E) Survival, (F) weight loss, and (G) clinical scores of mice on semi-purified diet treated with plain drinking water or drinking water with 0.125 mg/mL ciprofloxacin beginning 1 day after inoculation with 104 VPI 10463 C. difficile (n = 10 per group). All error bars show SEM. * P ≤ 0.05; ** P ≤ 0.01; *** P ≤ 0.001. Log-rank test used for survival analysis and two-tailed Student’s t-test or Mann-Whitney U test used for comparing averages.