Skip to main content
. 2017 Oct 20;292(51):20975–20988. doi: 10.1074/jbc.M117.806422

Figure 2.

Figure 2.

MEF2A-sensitive genes display cardiac chamber-specific dysregulation in adult MEF2A KO hearts. A, quantitative RT-PCR analysis revealed that Arhgef19, Chrdl2, Clic6, Itga7, and Shisa6 were preferentially dysregulated in adult MEF2A KO atria by more than 2-fold when compared with their expression in KO ventricles. Expression levels for each gene in KO atria and ventricles were normalized to their respective WT cardiac region. B, quantitative RT-PCR analysis revealed that Bex1, Fbxo44, Fgf16, Pknox2, and Slitrk4 were dysregulated in KO ventricles by more than 2-fold compared with KO atrial tissue. C, quantitative RT-PCR analysis revealed that Aqp4, Arhgap20, Asb4, Fgf14, and Pde7a were dysregulated by more than 1.5-fold in both KO atria and ventricles. Error bars represent standard deviation; *, p < 0.05; **, p < 0.01; ***, p < 0.001.