Figure 3.

Plasma RNLS levels drop dramatically with CER stimulation in vivo. Pancreatitis was induced in mice by six hourly injections of CER (50 μg/kg of body weight). At the indicated times after the first CER injection, plasma and pancreas were collected for determination of plasma RNLS levels by immunoblot analysis (A), plasma amylase levels (B), and tissue edema as determined by wet versus dry weight (C). White bars are control, which received only PBS. Black bars are CER-treated. *, p < 0.05 compared with PBS (white bar). n = 5 or more for each time point. Values represent the mean, and error bars represent the S.E. AVG, average.