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. 2017 Oct 5;292(51):21137–21148. doi: 10.1074/jbc.M117.819029

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© 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 4. — Effects of KIBRA and YAP overexpression on podocyte cytoskeleton and YAP localization. A, representative Western blots showing ectopic overexpression of KIBRA alone and co-overexpression of KIBRA and YAP in murine podocytes. B, representative immunofluorescence images showing actin (phalloidin), focal adhesions (paxillin), YAP, and nuclei (Hoechst 33342) for control, KIBRA OE, and KIBRA/YAP OE podocytes. Insets within the paxillin images show zoomed-in morphological characteristics of representative focal adhesion sites. Scale bar, 100 μm.