Figure 3.

Primary tongue specimen from cetuximab‐IRDye800 clinical trial data using microdose. A patient with a lateral tongue squamous cell carcinoma underwent systemic injection of cetuximab‐IRDye800 3 days prior to hemiglossectomy and cervical lymph node dissection. Tongue specimen (A) underwent 4‐mm punch biopsies peripheral (square) and proximal (circle) to the tumor (T). Brightfield imaging (B) and LUNA imaging (C) was performed in the operating room and subsequently imaged in Pathology using the PEARL (D). Histology was used to determine the absence (peripheral biopsy, square) or presence (proximal biopsy, circle) of tumor.