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. 2017 Nov 10;52(1):55–66. doi: 10.3892/ijo.2017.4200

Table III.

Evaluation of 12 selected miRNAs using sRNA sequencing and RT-qPCR methods.

miRNA Malignant vs. benign OGCTsa
Malignant OGCTs vs. SCSTsb
Benign OGCTs vs. SCSTsb
sRNA seq RT-qPCR Concordance sRNA seq RT-qPCR Concordance sRNA seq RT-qPCR Concordance
miR-372-3p Higher Higher Yes Higher Higher Yes Equal Equal Yes
miR-373-3p Higher Higher Yes Higher Higher Yes Equal Equal Yes
miR-302c-3p Higher Higher Yes Higher Higher Yes Higher Equal No
miR-199a-5p Lower Lower Yes Lower Lower Yes Equal Equal Yes
miR-214-5p Lower Lower Yes Lower Lower Yes Equal Equal Yes
miR-202-3p Lower Lower Yes Lower Lower Yes Lower Lower Yes
miR-513c-5p Equal Lower No Lower Lower Yes Lower Lower Yes
let-7f Lower Equal No Lower Equal No Equal Equal Yes
miR-21 Equal Equal Yes Higher Equal No Equal Equal Yes
miR-34a Higher Equal No Higher Equal No Equal Equal Yes
miR-125a-5p Equal Equal Yes Lower Equal No Equal Equal Yes
miR-193a-3p Higher Equal No Higher Equal No Higher Equal No
a

Higher and lower refer to expression in the malignant OGCTs compared to the benign OGCTs.

b

Higher and lower refer to expression in malignant or benign OGCTs as compared to SCSTs. miRNA, microRNA; OGCT, ovarian germ cell tumor; SCST, sex cord stromal tumor; sRNA seq, small RNA sequencing; RT-qPCR, reverse transcription-quantitative polymerase chain reaction.