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GPx3 significantly suppressed hepatic senescence in vitro and in vivo. (A) GPx3 delivered by hiPSC-MSCs significantly suppressed hepatic senescence in the mice IR injury model. Arrows indicated the positive signals of senescent hepatocytes. (B) rGPx3 significantly suppressed hepatic senescence of MIHA and LO2 cells in a dose dependent manner in vitro. Arrows indicated the positive signals of senescent hepatocytes.
