Table 1.
Four gene candidates were identified to be responsible for suppressive effect of GPx3 on hepatic senescence.
| Symbol | GenBank | UniGene | Description |
|---|---|---|---|
| Down-regulated | |||
| CD44 | NM_000610 | Hs.502328 | CD44 molecule (Indian blood group) |
| NOX4 | NM_016931 | Hs.371036 | NADPH oxidase 4 |
| IFNG | NM_000619 | Hs.856 | Interferon, gamma |
| SERPINB2 | NM_002575 | Hs.594481 | Serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
The Human Cellular Senescence RT² Profiler PCR Array profiles the expression of 84 key genes involved in the initiation and progression of the biological process causing cells to lose the ability to divide. This array includes genes involved in the primary senescence program and known stresses that cause premature senescence.