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. 2017 Dec 21;23(47):8277–8282. doi: 10.3748/wjg.v23.i47.8277

Table 1.

Studies with histologically documented cases of advanced liver disease in pediatric nonalcoholic fatty liver disease

Study Yr No. of patients Age (yr) Follow-up (yr) Case of cirrhosis Progression of fibrosis (n) Case of liver transplantation (n)
(n)
Cross-sectional studies
Kinugasa et al[17] 1984 299 N/A N/A 1 N/A N/A
Schwimmer et al[16] 2003 43 N/A N/A 1 N/A N/A
Suzuki et al[15] 2005 1 12 N/A 1 N/A N/A
Schwimmer et al[18] 2005 100 Range 2-18 N/A 3 N/A N/A
Alkhouri et al[19] 2012 203 Mean 12.4 N/A 0 N/A N/A
Longitudinal studies
Molleston et al[14] 2002 2 10 and 14 N/A 2 2/2 None
Feldstein et al[4] 2009 66 Mean 13.9 6.4 2 4/5 2
(5 followed longitudinally)
A-Kader et al[21] 2008 106 Range 7-19 2.3 2 7/18 N/A
(18 followed longitudinally)
Lavine et al[22] 2012 (preliminary report) 58 Range 8-17 1.8 N/A 15/58 N/A
Brunt et al[23] 2014 (preliminary report) 102 Range 11-17 2.2 N/A 20/102 N/A
Alkhouri et al[24] 2015 (preliminary report) 330 4-40 N/A N/A N/A 14/330

N/A: Not available.