Table 2.
Marrow collection procedures and yields.
| Variable | Marrow N (%) |
PBSC-Marrow N (%) |
Marrow-Marrow N (%) |
P-valuea |
|---|---|---|---|---|
| Number of donors | 5829 | 76 | 42 | |
|
| ||||
| Duration of anesthesia in minutes, first collection | ||||
| N Eval | 5706 | 0 | 39 | |
| Less than 60 minutes | 626 (11) | (N/A) | 12 (31) | <0.001 |
| Less than 120 minutes | 4548 (80) | (N/A) | 35 (90) | 0.120 |
| Less than 150 minutes, NMDP recommendation | 5295 (93) | (N/A) | 38 (97) | 0.263 |
| Less than 200 minutes | 5646 (99) | (N/A) | 39 (100) | 0.520 |
| Median (range) | 90 (25–355) | (N/A) | 71(50–198) | <0.001 |
| Duration of anesthesia in minutes, last collection | ||||
| N Eval | 5706 | 76 | 42 | |
| Less than 60 minutes | 626 (11) | 12(16) | 7 (17) | 0.211 |
| Less than 120 minutes | 4548 (80) | 59 (78) | 36(86) | 0.566 |
| Less than 150 minutes, NMDP recommendation | 5295 (93) | 71 (93) | 39 (93) | 0.978 |
| Less than 200 minutes | 5646 (99) | 75(99) | 41 (98) | 0.689 |
| Median (range) | 90 (25–355) | 86 (36–210) | 87(42–246) | 0.341 |
| Collection volume, first donation | 0.041 | |||
| <1 L | 2516 (44) | (N/A) | 25 (64) | |
| 1–1.5 L | 2447 (43) | (N/A) | 10(26) | |
| ≥1.5 L | 733 (13) | (N/A) | 4 (10) | |
| Unknown | 133 (N/A) | (N/A) | 3 (N/A) | |
| Median (range), in mL | 1063.2 (103.0–2323.0) | (N/A) | 668.0 (193.0–1921.0) | <0.001 |
| Collection volume, last donation | 0.014 | |||
| <1 L | 2516 (44) | 27(36) | 27 (68) | |
| 1–1.5 L | 2447 (43) | 41 (54) | 10 (25) | |
| ≥1.5 L | 733 (13) | 8 (11) | 3 (8) | |
| Unknown | 133 (N/A) | 0 (N/A) | 2 (N/A) | |
| Median (range), in mL | 1063.2 (103.0–2323.0) 111 | 6.0 (364.0–1780.0) | 813.0 (276.0–1648.0) | 0.010 |
| Collection volume per kg of donor weight, first donation | 0.005 | |||
| <10/kg | 1700 (30) | (N/A) | 22 (56) | |
| 10 to <15/kg | 1834 (32) | (N/A) | 8 (21) | |
| 15 to <20/kg | 1769 (31) | (N/A) | 7 (18) | |
| ≥20/kg | 375 (7) | (N/A) | 2 (5) | |
| Unknown | 151(N/A) | (N/A) | 3 (N/A) | |
| Median (range) | 13.2 (1.2–29.0) | (N/A) | 8.5 (2.2–20.5) | <0.001 |
| Collection volume per kg of donor weight, last donation | 0.089 | |||
| <10/kg | 1700 (30) | 20(26) | 21 (53) | |
| 10 to <15/kg | 1834 (32) | 25 (33) | 10 (25) | |
| 15 to <20/kg | 1769 (31) | 27(36) | 7 (18) | |
| ≥20/kg | 375 (7) | 4 (5) | 2 (5) | |
| Unknown | 151(N/A) | 0 (N/A) | 2 (N/A) | |
| Median (range) | 13.2 (1.2–29.0) | 13.9 (4.2–21.6) | 9.7 (3.2–22.6) | 0.007 |
| TNC (×108), first donation | ||||
| N Eval | 2887 | 0 | 19 | |
| Median (range) | 24194.3 (2596.8–26657440) | (N/A) | 19669.0 (5747.8–40750.0) | 0.024 |
| TNC (×108), last donation | ||||
| N Eval | 2887 | 40 | 17 | |
| Median (range) | 24194.3 (2596.8–26657440) | 26832.9 (8095.5–54504.9) | 13276.9 (6206.0–23708.4) | <0.001 |