. Author manuscript; available in PMC: 2019 Jan 1.

Published in final edited form as: Biol Blood Marrow Transplant. 2017 Sep 25;24(1):175–184. doi: 10.1016/j.bbmt.2017.09.013

Table 6.

Prognostic factor analysis for selected outcomes of second PBSC donations.

Variable	MTC grade 2–4 during collection		Skeletal pain grade 2–4 during collection		Recovery to Baseline
Variable	OR (95 %CI)	p-value	OR (95 %CI)	p-value	HR (95 %CI)	p-value

Group		0.040		0.031
PBSC-PBSC	1.00		1.00
Marrow-PBSC	1.70 (1.02–2.82)		1.50 (1.04–2.17)

Group/time to recovery after 1^st donation						<0.001
PBSC-PBSC, Recovery ≤3d					1.00
PBSC-PBSC, Recovery 4–14d					0.69 (0.54–0.89)	0.004
PBSC-PBSC, Recovery >14d					0.44 (0.33–0.59)	<0.001
Marrow-PBSC					0.60 (0.48–0.77)	<0.001

Max MTC grade during collection of 1^st donation		<0.001		0.040		0.031
0–1	1.00		1.00		1.00
2–4	3.29 (2.06–5.26)	<0.001	1.93 (1.16–3.20)	0.011	0.75 (0.61–0.93)	0.009
Unknown	0.69 (0.19–2.48)	0.574	1.16 (0.07–20.05)	0.916	0.91 (0.58–1.43)	0.686

Skeletal pain grade during collection of 1^st donation				<0.001
0–1			1.00
2–4			2.74 (1.86–4.04)	<0.001
Unknown			1.16 (0.07–20.05)	0.916

BMI (kg/m²)		<0.001
Underweight/normal, <24.9	1.00
Overweight, 25–29.9	2.79 (1.58–4.92)	<0.001
Obese, 30+	2.99 (1.67–5.36)	<0.001

Interval between collections						0.006
≤12 months					1.00
>12 months					0.79 (0.66–0.93)