Table 1.
Clinico-pathological correlation of the expression of miR193a-3p in an ovarian cancer tissue array (OVC1021). The 4-fold and 3-fold cut-off points of miR-193a-3p and GRB7, respectively, were determined by ROC analysis.
| Parameters n(=97) | miR-193a-3p expression | |||
|---|---|---|---|---|
| ≤ 4-fold | >4-fold | p | ||
| Grade | ||||
| Low (1+2) | 50 | 31 (62%) | 19 (38%) | |
| High (3) | 46 | 37 (80%) | 9 (20%) | 0.071 |
| Stage | ||||
| Early (1) | 48 | 29 (60%) | 19 (40%) | |
| Late (2+3) | 49 | 39 (80%) | 10 (20%) | 0.048* |
| Metastasis | ||||
| Yes | 24 | 20 (83%) | 4 (17%) | |
| No | 73 | 48 (66%) | 25 (34%) | 0.127 |
| GRB7 | ||||
| ≤ 3 folds | 38 | 20 (53%) | 18 (47%) | |
| > 3 folds | 59 | 48 (81%) | 11 (19%) | 0.003* |