Figure 3.
The metabolic events leading to altered very-low density lipoprotein (VLDL) secretion in NAFLD. While increased synthesis of ApoB100 leads to enhanced VLDL secretion in steatosis, oxidative stress-induced degradation of ApoB100 may result in reduced VLDL secretion in NASH. TG; triglyceride, ROS; reactive oxygen species, FAO; fatty acid oxidation.
