Figure 1.

Plasma triglyceride levels and adipocyte density in iWAT of female and male F344 offspring following developmental bisphenol A (BPA) exposure. Effects of developmental exposure to 0.5 (BPA0.5), 50 (BPA50), or $0\left(\mathrm{CTRL}\right)\mathrm{\mu }\mathrm{g}\text{BPA}/\mathrm{kg}\text{BW}/\text{d}$; BPA0.5, BPA50, CTRL on (A) plasma triglyceride levels (mmol/L) in five-wk-old female and male F344 offspring and dams (females, $\mathit{n}=30$: CTRL, $\mathit{n}=13$; BPA0.5, $\mathit{n}=10$; BPA50, $\mathit{n}=7$); the Kruskal–Wallis test was used to calculate the difference between groups and p-values from Dunnett's test are shown in the figure (males, $\mathit{n}=33$: CTRL, $\mathit{n}=13$; BPA0.5, $\mathit{n}=11$; BPA50, $\mathit{n}=9$); analysis of variance (ANOVA)/Dunnett’s test was used to calculate the difference between groups and p-values from Dunnett's test are shown in the figure. (B) Average number of iWAT fat cells per high power field in female and male F344 offspring [postnatal day (PND)35] (females, $\mathit{n}=18$ CTRL, $\mathit{n}=6$; BPA0.5, $\mathit{n}=6$; BPA50, $\mathit{n}=6$; males, $\mathit{n}=18$; CTRL, $\mathit{n}=6$; BPA0.5, $\mathit{n}=6$; BPA50, $\mathit{n}=6$), ANOVA/Dunnett’s test was used to calculate the difference between groups. Values are shown as the $\text{means}\pm \text{SEM}$. Note: F344, Fischer 344 rat; iWAT, inguinal white adipose tissue. * $\mathit{p}<0.05$ ** $\mathit{p}<0.01$.