Figure 3.

Transciptional levels in gWAT and iWAT of female and male F344 offspring following BPA exposure. Effects of developmental exposure to 0.5, 50, or $0\mathrm{\mu }\mathrm{g}\text{BPA}/\mathrm{kg}\text{BW}/\text{d}$ (BPA0.5, BPA50, and CTRL, respectively) in five-wk-old F344 offspring on the relative mRNA expression of (A) AdipoR1, AdipoR2, LPL, SCD1, ACC, GATA2 and SREBP-1c in male gWAT (B) AdipoR1, AdipoR2, LPL, SCD1, ACC, GATA2 and SREBP-1c in female gWAT (C) AdipoR1 and SCD1 in male iWAT (D) AdipoR1 and SCD1 in female iWAT (females, $\mathit{n}=29$: CTRL, $\mathit{n}=13$; BPA0.5, $\mathit{n}=10$; BPA50, $\mathit{n}=6$; males, $\mathit{n}=32$: CTRL, $\mathit{n}=12$; BPA0.5, $\mathit{n}=10$; BPA50, $\mathit{n}=10$). ANOVA/Dunnett’s test was used to calculate the difference between groups. Values are shown as the $\text{means}\pm \text{SEM}$. Note: ACC, acetyl-CoAa carboxylase; AdipoR, adiponectin receptor (1 and 2); F344, Fischer 344 rat; GATA2, G protein-coupled estrogen receptor 1; iWAT, inguinal white adipose tissue; LPL, lipoprotein lipase; SCD1, stearoyl-CoA desaturase; SREBP-1c, sterol regulatory element binding protein-1c. * $\mathit{p}<0.05$; # One-way ANOVA for all groups.