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Effects of PD-1 antibodies on peripheral blood lymphocyte proportion. A and D: During immunotherapy, the proportion of total CD3+ T lymphocyte and CD3-CD16+CD56+ natural killer cells remained unchanged. B and C: In the subset analysis, the proportion of CD3+CD4+ T lymphocytes seem to show a downward trend, while the proportion of CD3+CD8+-T lymphocytes show an upward trend in patients with stable disease.
