Figure 2.

Classification of mammalian protein phosphatase families and their relevance for Leishmania infection. Protein phosphatases are classified depending on their structural features and their substrate specificity. The two main families of protein phosphatases and their respective subfamilies are depicted here. Serine threonine phosphatases are marked with red initials, whereas protein tyrosine phosphatases are given with blue initials. Host protein phosphatases which were already shown to affect the outcome of Leishmania infections are written in bold and italic black letters.