Table 1.
Effect of carnosine (CAR) treatment on initial and final body weights, body weight gain, liver weight and liver index (liver weight ×100/final body weight) in high‐fat diet and low dose of streptozotocin (HFD+STZ)‐treated rats (Mean ± SD)
| Parameters | Control (n = 6) | CAR (n = 6) | HFD+STZ (n = 8) | HFD+STZ+CAR (n = 8) |
|---|---|---|---|---|
| Initial body weight (g) | 204.7 ± 8.04 | 205.0 ± 8.94 | 211.6 ± 11.1 | 202.4 ± 7.00 |
| Final body weight (g) | 292.5 ± 18.9 | 295.8 ± 17.7 | 254.9 ± 35.7 | 259.2 ± 38.9 |
| Body weight gain (g/12 weeks) | 87.8 ± 15.9 | 90.8 ± 12.0 | 43.2 ± 27.3* | 56.9 ± 32.7 |
| Liver weight (g) | 7.66 ± 0.37 | 7.58 ± 0.30 | 8.02 ± 0.58 | 7.77 ± 0.73 |
| Liver index (%) | 2.62 ± 0.07 | 2.56 ± 0.06 | 3.20 ± 0.49* | 3.06 ± 0.60** |
*P < 0.01; **P < 0.05 as compared to the control group.