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The cPLA2 family. (A) Structures of cPLA2 enzymes (α-ζ). The C2 domain, which is essential for Ca2+-dependent membrane translocation, is conserved in cPLA2 enzymes except for cPLA2γ, whose C-terminal region is farnesylated. (B) A schematic diagram of stimulus-induced cPLA2α activation. For details, see the text.
