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. 2017 Dec 22;8:947. doi: 10.3389/fphar.2017.00947

FIGURE 2.

FIGURE 2

Structure of various synthetic agonist (38–41) and antagonist (42–52) ligands for the P2YRs and P2XRs, as described in the text. Compound 52 was introduced as an antihistamine and later found to block the P2X7R.