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. 2017 Dec 22;4:232. doi: 10.3389/fvets.2017.00232

Table 2.

Performance characteristics of intestinal tissue and mesenteric lymph node (MLN) quantitative PCR (qPCR) with reference to tissue culture and tissue histopathological lesion results.

Test Tissue Reference test Se [95% confidence interval (CI)]a PDLR (95% CI)b
qPCR Intestine Culture 88.34 (80.22, 96.46) 3.78 (2.24, 6.39)
Histopathological lesions 85.72 (75.92, 95.52) 2.53 (1.71, 3.74)
MLN Culture 86.45 (77.71, 95.18) 2.19 (1.52, 3.15)
Histopathological lesions 81.82 (71.63, 92.02) 1.99 (1.38, 2.86)
Bothc Culture 95.32 (90.14, 100.00) 2.16 (1.54, 3.04)
Histopathological lesions 89.66 (81.82, 97.50) 1.72 (1.28, 2.31)

aSe = estimated test sensitivity in percentage and 95% CI of the estimate.

bPositive diagnostic likelihood ratio and CI.

cParallel test results of both tissues were compared with parallel test results of the reference tests for both tissues.