Table 1.
Refined classification by IHC of 328 cases originally diagnosed at UOMCOM by H&E only
| Original pathologic classification | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Refined diagnosis incorporating IHC | DLBCL/high-grade NHL (n = 116) | BL (n = 70) | CLL/SLL (n = 7) | MZL (n = 2) | PBL (n = 2) | LBL (n = 1) | FL (n = 3) | ALCL (n = 2) | PCN (n = 1) | NHL/low-grade NHL/lymphoma NOS/low-grade BCL (n = 101) | Suspicious for NHL (n = 23) |
| DLBCL (n = 133) | 70 | 8 | — | — | — | — | 1 | 1 | 1 | 45 | 7 |
| BL (n = 73) | 12 | 43 | — | — | — | — | — | — | — | 14 | 4 |
| BCL (n = 27) | 6 | 2 | 2 | — | — | — | 2 | — | — | 14 | 1 |
| PBL (n = 20) | 11 | 5 | — | — | — | 1 | — | — | — | 2 | 1 |
| Neuroendocrine tumor (n = 20) | 4 | 6 | — | — | — | — | — | — | — | 6 | 4 |
| BCL-U (n = 9) | 4 | 3 | 1 | — | 1 | — | — | — | — | — | — |
| T-ALL (n = 8) | 2 | 1 | — | — | — | — | — | — | — | 3 | 2 |
| Carcinoma NOS (n = 8) | 2 | — | — | — | — | — | — | — | — | 6 | — |
| CLL/SLL (n = 7) | 1 | — | 4 | — | — | — | — | — | — | 2 | — |
| MZL (n = 5) | 1 | — | — | 2 | — | — | — | — | — | — | 2 |
| CHL (n = 4) | 1 | 1 | — | — | — | — | — | 1 | — | 1 | — |
| FL (n = 3) | 2 | — | — | — | — | — | — | — | — | 1 | — |
| Myeloid sarcoma (n = 2) | — | — | — | — | — | — | — | — | — | 2 | — |
| MCL (n = 2) | — | — | — | — | — | — | — | — | — | 2 | — |
| ALK + ALCL (n = 2) | — | — | — | — | — | — | — | — | — | 1 | 1 |
| Plasmacytoma (n = 2) | — | — | — | — | 1 | — | — | — | — | 1 | — |
| PTCL NOS (n = 1) | — | 1 | — | — | — | — | — | — | — | — | — |
| Nasopharyngeal carcinoma (n = 1) | — | — | — | — | — | — | — | — | — | — | 1 |
| Reactive (n = 1) | — | — | — | — | — | — | — | — | — | 1 | — |
ALCL, anaplastic large cell lymphoma; BCL, B-cell lymphoma not further classified; CLL/SLL, chronic lymphocytic leukemia/small lymphocytic lymphoma; FL, follicular lymphoma; LBL, lymphoblastic lymphoma; MCL, mantle cell lymphoma; MZL, marginal zone lymphoma; NOS, not otherwise specified; PBL, plasmablastic lymphoma; PCN, plasma cell neoplasm; PTCL, peripheral T-cell lymphoma; T-ALL, T-lymphoblastic lymphoma.