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. 2017 Dec 22;8:1922. doi: 10.3389/fimmu.2017.01922

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Copyright © 2017 Hammer, Waschbisch, Knippertz, Zinser, Berg, Jörg, Kuhbandner, David, Pi, Bayas, Lee, Haghikia, Gold, Steinkasserer and Linker.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) affects maturation marker expression of human dendritic cell (DC) in vitro. Frequency of CD80 (A), CD86 (B), MHCI (C), MHCII (D), CD25 (E), CD83 (F), CCR7 (G), and ILT-4 (H) positive cells in total human monocyte-derived DC under metabolite monomethyl fumarate (MMF) treatment as assessed by flow cytometry. The immature control group was not treated with the maturation cocktail as described in the method section. Statistical significance was tested between the matured, untreated control group (ctrl) and the MMF-treated groups (data pooled from four to five independent experiments, *p < 0.05, **p < 0.01, ***p < 0.001).