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. 2017 Dec 15;5(4):70. doi: 10.3390/biomedicines5040070

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© 2017 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Characterization of protein corona on AuNP surface. (Top) Effects of ethanol exposure on composition of corona proteins. (Bottom left) Chromatographic separation of peptides extracted from ethanol-negative cells. (Bottom right) Chromatographic separation of peptides extracted from ethanol-positive cells. Protein identification: 1: alcohol dehydrogenase, 2: cAMP/cGMP phosphodiesterase, 3: Tyr phosphatase, 4: transferrin, 5: glutamate CoA phosphodiesterase, 6: arginine N-methyltransferase, 7: casein kinase, 8: MAPK kinase-9, and 10: parvalbumin. C₀: control cells, C16: control cells exposed for 16 days; ADH: alcohol dehydrogenase; cAMP: cyclic adenosine dinucleotide mono phosphate; cGMP: cyclic guanine dinucleotide mono phosphate; MAPK: mitogen activated protein kinase; CPS: cAMP/gAMP phosphodiesterase.