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. 2017 Dec 22;8:724. doi: 10.3389/fneur.2017.00724

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Copyright © 2017 Klehmet, Staudt, Diederich, Siebert, Meinl, Harms and Meisel.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) MRI shows pontocerebellar lesion with incomplete peripheral enhancement. (B) Elevated IFNγ response against neurofascin (NF)155 and NF186 before clinical manifestation in Elispot assay. (C) Follow-up MRI shows new lesion in the middle cerebellar peduncle and adjacent pons without clinical manifestation or contrast enhancement. (D) Follow-up Elispot assay shows no IFNγ response against NF.