FIG 5.

Probability of shedding is not associated with the genotype at codon 96 or with sex. (A) We compared the probabilities of prion shedding in saliva from deer homozygous for glycine at codon 96 (GG, the more susceptible genotype) and deer heterozygous at codon 96 (GS, the more resistant genotype). The values are derived from male deer inoculated with saliva via the oral route. (B) We compared the probabilities of prion shedding in saliva between male and female deer. The values are derived from GG deer inoculated with saliva via the oral route. Violin plots portray our knowledge of the effect of sex or genotype on prion shedding. The widths of the violins are proportional to the probabilities of a particular value of shedding probability being the true value, and the heights of the violins span the 95% credible intervals for the probability of shedding (i.e., there is a 95% probability that the true values of prion shedding are encompassed by the violins). The dots represents the posterior means and are a point estimate for shedding probability in each case.