TABLE 3.
Proportion of positive tests for 28 serum samples collected from 20 tularemia patients at different time intervals from the onset of clinical symptoms
| Method (cutoff titer) | % positive tests (no. positive serum samples/no. tested) at: |
||||
|---|---|---|---|---|---|
| 1st wk | 2nd wk | 3rd and 4th wks | 2nd mo | Overall | |
| MAT (≥80) | 0 (0/7) | 33.3 (2/6) | 75 (6/8) | 85.7 (6/7) | 50 (14/28) |
| IFA-IgM (≥80) | 0 (0/7) | 33.3 (2/6) | 62.5 (5/8) | 85.7 (6/7) | 46.4 (13/28) |
| IFA-IgG (≥160) | 0 (0/7) | 0 (0/6) | 87.5 (7/8) | 100 (7/7) | 50 (14/28) |
| ELISA-IgM (OD ≥ 0.45) | 14.3 (1/7) | 66.7 (4/6) | 100 (8/8) | 100 (7/7) | 71.4 (20/28) |
| ELISA-IgM (OD ≥ 0.9) | 14.3 (1/7) | 66.7 (4/6) | 100 (8/8) | 100 (7/7) | 71.4 (20/28) |
| ELISA-IgG (OD ≥ 0.62) | 0 (0/7) | 66.7 (4/6) | 100 (8/8) | 100 (7/7) | 67.8 (19/28) |
| ELISA-IgG (OD ≥ 1.4) | 0 (0/7) | 33.3 (2/6) | 100 (8/8) | 100 (7/7) | 60.7 (17/28) |
| VIRapid (band intensity ≥ 0.5) | 14.3 (1/7) | 33.3 (1/3) | 100 (4/4) | 100 (7/7) | 61.9 (13/21) |