TABLE 2.
Adjusted rates of inpatient infections of S. aureus by subtype and antibiogram type per 1,000 inpatients in 2003 and 2014
| Subtype or antibiogram type | Rate of infections/1,000 inpatients (% [95% CI])b |
Annual % change (95% CI) in countsb | P value | |
|---|---|---|---|---|
| 2003 | 2014 | |||
| Subtype | ||||
| All S. aureus | 33.4 (23.5–43.3) | 21.3 (11.5–31.2) | −4.2 (−5.6 to −2.7) | <0.0001 |
| MRSA | 21.1 (17.0–25.1) | 6.3 (2.2–10.4) | −10.9 (−12.6 to −9.3) | <0.0001 |
| MSSA | 11.1 (9.0–13.3) | 10.3 (8.2–12.5) | −0.6 (−2.1 to 0.9) | 0.43 |
| PSSA | 1.9 (1.2–2.7) | 4.0 (3.2–4.7) | 6.1 (4.2 to 8.1) | <0.0001 |
| Antibiogram typea | ||||
| PMEL | 15.8 (12.6–19.0) | 4.9 (1.7–8.1) | −12.1 (−13.6 to −10.5) | <0.0001 |
| PME | 1.0 (0.1–1.9) | 1.4 (0.4–2.3) | 3.0 (−0.1 to 6.2) | 0.06 |
| PE | 3.2 (3.0–3.5) | 2.8 (2.6–3.1) | −1.4 (−3.2 to 0.5) | 0.14 |
| P | 6.2 (4.8–7.6) | 6.0 (4.6–7.4) | −0.3 (−2.3 to 1.8) | 0.80 |
| Pansusceptible | 1.3 (0.8–1.7) | 2.3 (1.9–2.8) | 5.3 (3.1 to 7.5) | <0.0001 |
| Other | 3.9 (1.8–6.0) | 6.0 (3.9–8.0) | 3.3 (0.2 to 6.4) | 0.04 |
a
Antibiogram types exclude clindamycin. “Other” category includes all antibiograms not belonging to top 5 most common antibiogram types. PMEL, penicillin-, methicillin-, erythromycin-, and levofloxacin-resistant S. aureus; PME, penicillin-, methicillin-, and erythromycin-resistant S. aureus; PE, penicillin- and erythromycin-resistant S. aureus; P, penicillin-resistant S. aureus.
b
Percentage estimates adjusted for age, sex, Charlson comorbidity index, type of clinical isolate (blood versus nonblood), and onset (community versus hospital).