Table 3.
Effect sizes for differences in neurocognitive performances by IDH1 status
| Domain and Test | IDH1 Wild Type | IDH1 Mutant | Effect Sizea | P valueb | ||
|---|---|---|---|---|---|---|
| N | z-score M (SD) | N | z-score M (SD) | |||
| Attention | ||||||
| Digit Span | 63 | –0.39 (0.93) | 53 | –0.18 (1.03) | –0.29 | .250 |
| Learning and Memory | ||||||
| HVLT-R TR | 63 | –1.71 (1.73) | 51 | –0.99 (1.42) | –0.45 | .018* |
| HVLT-R DR | 10 | –2.53 (1.32) | 22 | –1.03 (1.55) | –1.04 | .013* |
| HVLT-R Recog | 10 | –1.02 (1.43) | 22 | –0.54 (1.66) | –0.30 | .434 |
| Processing Speed | ||||||
| Digit Symbol | 62 | –0.51 (1.05) | 53 | 0.56 (0.81) | –0.61 | .002* |
| TMTA | 63 | –1.34 (2.93) | 53 | –0.01 (1.00) | –0.63 | .001* |
| Executive Function | ||||||
| TMTB | 55 | –2.26 (3.23) | 53 | –0.85 (2.06) | –0.52 | .008* |
| Similarities | 62 | –0.42 (1.04) | 52 | –0.25 (0.84) | –0.18 | .331 |
| COWA | 66 | –1.23 (1.47) | 50 | –0.64 (1.32) | –0.43 | .025* |
| Language | ||||||
| Token | 64 | –0.33 (1.32) | 49 | 0.27 (0.97) | –0.53 | .006* |
| Naming | 61 | –0.52 (1.18) | 50 | –0.24 (0.87) | –0.28 | .147 |
| Visuospatial Function | ||||||
| Block Design | 63 | –0.36 (1.11) | 52 | –0.06 (0.91) | –0.30 | .118 |
| Motor Function | ||||||
| Peg- Left | 60 | –1.60 (3.19) | 51 | –0.35 (1.07) | –0.54 | .006* |
| Peg- Right | 62 | –1.97 (4.03) | 52 | –0.33 (1.18) | –0.57 | .003* |
aEffect sizes represent Cohen’s d.
bIndependent samples t-tests used for group comparisons.
*Significant, P ≤ .05.