Table 1.
Estimated global distribution of retinoblastoma.
| Category | Population, total | Birth rate, crude (per 1,000 people) | Mortality rate, infant (per 1,000 live births) | Forecast live birth total | Retinoblastoma incidence (high) 1:16,000 | Retinoblastoma incidence (low) 1:18000 | % of world retinoblastoma |
|---|---|---|---|---|---|---|---|
| World | 7 × 109 | 19.4 | 34.6 | 131 106 | 8,200 | 7,300 | 100% |
| High income | 1,299,489,520 | 11.6 | 5.5 | 14,941,320 | 934 | 830 | 11.4% |
| High income: non-OECD | 249,927,994 | 13.8 | 10.3 | 3,418,872 | 214 | 190 | not applicable |
| High income: OECD | 1,049,561,526 | 11.0 | 4.4 | 11,518,845 | 720 | 640 | not applicable |
| Low & middle income | 5,743,616,071 | 21.1 | 38.1 | 116,699,203 | 7,294 | 6,483 | 88.7% |
| Middle income | 4,913,580,797 | 19.2 | 33.7 | 91,300,546 | 5,706 | 5,072 | 69.4% |
| Upper middle income | 2,390,210,774 | 14.8 | 16.3 | 34,737,317 | 2,171 | 1,930 | 26.4% |
| Lower middle income | 2,523,370,023 | 23.4 | 45.3 | 56,490,388 | 3,531 | 3,138 | 42.9% |
| Low income | 830,035,274 | 32.3 | 54.5 | 25,373,890 | 1,586 | 1,410 | 19.3% |
Forecast births were calculated using most recent data (2012) on each World Bank Category for population, birth rate and mortality rate (World Bank (http://data.worldbank.org) accessed on 5 February 2015. Low (1:18,000 live births) and high estimates (1:16,000 live births) for retinoblastoma were calculated, following the example of Kivela.5 Since retinoblastoma arises before and near birth, the usual cancer incidence rate calculations (number of cases diagnosed in a given population, sometimes adjusted for the under-514 or under-1411 populations in children’s cancers) do not provide accurate data for retinoblastoma. OECD, Organisation for Economic Co-operation and Development