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In vivo non-invasive near-infrared (NIR) absorption images of real-time tumor specificity of cRGD-PGNRs. (A) In vivo time-dependent brain region biodistribution of cRGD-PGNRs and cRAD-PGNRs as a control; (B) relative photon counts of in vivo tumor target specificity of cRGD-PGNRs (square) and cRAD-PGNRs (circle) was recorded; and (C) relative quantification of in vivo biodistribution of cRGD-PGNRs and cRAD-PGNRs in different tissues [81].
