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. 2017 Dec 26;13:14. doi: 10.1186/s12993-017-0132-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Gestational exposure to isoflurane resulted in region-specific cell loss in the adult hippocampus. No changes were detected in the pyramidal layer of the CA1 area of adult male rats following isoflurane exposure in utero (N = 13) compared to control rats (N = 10) (a). However, isoflurane exposure at E14 (N = 13) was associated with a significant decrease in the number of cells in the granule cell layer of the dentate gyrus (*P = 0.01) compared to control rats (N = 10) (b). Data were analyzed using Student’s t-test and expressed as mean ± S.D