Table 3.
Correlations between Iba1 expression levels and expression of each synaptic protein
| Comparison, age, and genotype | Nucleus | Correlation coefficient and statistics |
|---|---|---|
| Iba1 vs. VGLUT | ||
| P6 | ||
| Wild type | VCN | Pearson’s r = 0.781; p = 0.038; n = 7 |
| Wild type | MNTB | Pearson’s r = 0.818; p = 0.013; n = 8 |
| Wild type | LSO | Pearson’s r = 0.664; p = 0.073; n = 8 |
| Fmr1 KO | VCN | Pearson’s r = 0.386; p = 0.271; n = 10 |
| Fmr1 KO | MNTB | Pearson’s r = 0.793; p = 0.001; n = 13 |
| Fmr1 KO | LSO | Pearson’s r = 0.305; p = 0.310; n = 13 |
| P14 | ||
| Wild type | VCN | Pearson’s r = –0.179; p = 0.620; n = 10 |
| Wild type | MNTB | Pearson’s r = 0.493; p = 0.148; n = 10 |
| Wild type | LSO | Pearson’s r = –0.036; p = 0.921; n = 10 |
| Fmr1 KO | VCN | Pearson’s r = 0.176; p = 0.515; n = 16 |
| Fmr1 KO | MNTB | Pearson’s r = –0.039; p = 0.887; n = 16 |
| Fmr1 KO | LSO | Pearson’s r = –0.392; p = 0.133; n = 16 |
| Iba1 vs. VGAT | ||
| P6 | ||
| Wild type | VCN | Pearson’s r = 0.119; p = 0.799; n = 7 |
| Wild type | MNTB | Pearson’s r = 0.737; p = 0.037; n = 8 |
| Wild type | LSO | Pearson’s r = 0.236; p = 0.574; n = 8 |
| Fmr1 KO | VCN | Pearson’s r = 0.0006; p = 0.999; n = 10 |
| Fmr1 KO | MNTB | Pearson’s r = 0.695; p = 0.008; n = 13 |
| Fmr1 KO | LSO | Pearson’s r = 0.130; p = 0.673; n = 13 |
| P14 | ||
| Wild type | VCN | Pearson’s r = 0.097; p = 0.789; n = 10 |
| Wild type | MNTB | Pearson’s r = 0.149; p = 0.682; n = 10 |
| Wild type | LSO | Pearson’s r = –0.292; p = 0.412; n = 10 |
| Fmr1 KO | VCN | Pearson’s r = 0.165; p = 0.541; n = 16 |
| Fmr1 KO | MNTB | Pearson’s r = –0.345; p = 0.190; n = 16 |
| Fmr1 KO | LSO | Pearson’s r = –0.401; p = 0.124; n = 16 |
| Iba1 vs. Synaptophysin | ||
| P6 | ||
| Wild type | VCN | Pearson’s r = 0.422; p = 0.346; n = 7 |
| Wild type | MNTB | Pearson’s r = 0.006; p = 0.989; n = 7 |
| Wild type | LSO | Pearson’s r = 0.605; p = 0.150; n = 7 |
| Fmr1 KO | VCN | Pearson’s r = 0.281; p = 0.500; n = 8 |
| Fmr1 KO | MNTB | Pearson’s r = 0.231; p = 0.582; n = 8 |
| Fmr1 KO | LSO | Pearson’s r = 0.203; p = 0.629; n = 8 |
| P14 | ||
| Wild type | VCN | Pearson’s r = –0.115; p = 0.751; n = 10 |
| Wild type | MNTB | Pearson’s r = 0.346; p = 0.328; n = 10 |
| Wild type | LSO | Pearson’s r = 0.151; p = 0.676; n = 10 |
| Fmr1 KO | VCN | Pearson’s r = 0.565; p = 0.113; n = 9 |
| Fmr1 KO | MNTB | Pearson’s r = –0.057; p = 0.884; n = 9 |
| Fmr1 KO | LSO | Pearson’s r = –0.729; p = 0.026; n = 9 |